Posts Tagged ‘argumentation ontologies’

Linked Science 2014 paper: Using the Micropublications ontology and the Open Annotation Data Model to represent evidence within a drug-drug interaction knowledge base

October 19th, 2014

Today I’m presenting a talk in the ISWC 2014 Workshop on Linked Science 2014—Making Sense Out of Data (LISC2014). The LISC2014 paper is joint work with Paolo Ciccarese, Tim Clark and Richard D. Boyce. Our goal is to make the evidence in a scientific knowledge base easier to access and audit — to make the knowledge base easier to maintain as scientific knowledge and drug safety regulations change. We are modeling evidence (data, methods, materials) from biomedical communications in the medication safety domain (drug-drug interactions).

The new architecture for the drug-drug interaction knowledge base is based on:

This is part of a 4-year National Library of Medicine project, “Addressing gaps in clinically useful evidence on drug-drug interactions” (1R01LM011838-01)

Abstract of our paper, “Using the Micropublications ontology and the Open Annotation Data Model to represent evidence within a drug-drug interaction knowledge base.”:

Semantic web technologies can support the rapid and transparent validation of scientific claims by interconnecting the assumptions and evidence used to support or challenge assertions. One important application domain is medication safety, where more efficient acquisition, representation, and synthesis of evidence about potential drug-drug interactions is needed. Exposure to potential drug-drug interactions (PDDIs), defined as two or more drugs for which an interaction is known to be possible, is a significant source of preventable drug-related harm. The combination of poor quality evidence on PDDIs, and a general lack of PDDI knowledge by prescribers, results in many thousands of preventable medication errors each year. While many sources of PDDI evidence exist to help improve prescriber knowledge, they are not concordant in their coverage, accuracy, and agreement. The goal of this project is to research and develop core components of a new model that supports more efficient acquisition, representation, and synthesis of evidence about potential drug-drug interactions. Two Semantic Web models—the Micropublications Ontology and the Open Annotation Data Model—have great potential to provide linkages from PDDI assertions to their supporting evidence: statements in source documents that mention data, materials, and methods. In this paper, we describe the context and goals of our work, propose competency questions for a dynamic PDDI evidence base, outline our new knowledge representation model for PDDIs, and discuss the challenges and potential of our approach.

Citation: Schneider, Jodi, Paolo Ciccarese, Tim Clark, and Richard D. Boyce. “Using the Micropublications ontology and the Open Annotation Data Model to represent evidence within a drug-drug interaction knowledge base.” Linked Science 2014 at ISWC 2014.

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Posted in information ecosystem, scholarly communication, semantic web | Comments (0)

“Like” and its misuse

October 20th, 2010

Language evolves, and we use words loosely. But I’m more and more disturbed with the way “Like” is being manhandled.
A misuse of the Like button
Argumentation will need to encompass polarity; so I hope that it can help.

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Posted in argumentative discussions, PhD diary, random thoughts | Comments (4)

CiTO in the wild

October 18th, 2010

CiTO has escaped the lab and can now be used either directly in the CiteULike interface or with CiteULike machine tags. Go Citation Typing Ontology!

In the CiteULike Interface

To add a CiTO relationship between articles using the CiteULike interface, both articles must be in your own library. You’ll see a a “Citations (CiTO)” section after your tags. Click on edit and set the current article as the target.

set the CiTO target

First set the CiTO target

Then navigate around your own library to find a related article. Now you can add a CiTO tag.

Adding a CiTO tag in CiteULike

Adding a CiTO tag in CiteULike

There are a lot of choices. Choose just one. :)

CiTO Object Properties appear in the dropdown

CiTO Object Properties now appear in the dropdown

Congratulations, you’ve added a CiTO relationship! Now mousing over the CiTO section will show details on the related article.

CiTO result

Mouse over the resulting CiTO tag to get details of the related article

Machine Tags

Machine tags take fewer clicks but a little more know-how. They can be added just like any other tag, as long as you know the secret formula: cito--(insert a CiTO Object Property here from this list)--(insert article permalink numbers here) Here are two more concrete examples.

First, we can keep a list of articles citing a paper. For example, tagging an article


says “this article CiTO:cites article 137511”. Article 137511 can be found at, aka JChemPaint – Using the Collaborative Forces of the Internet to Develop a Free Editor for 2D Chemical Structures. Then we can get the list of (hand-tagged) citations to the article. Look—a community generated reverse citation index!

Second, we can indicate specific relationships between articles, whether or not they cite each other. For example, tagging an article


says “this item CiTO:usesmethodin item 42338”. Item 42338 is found at, aka The Chemistry Development Kit (CDK):  An Open-Source Java Library for Chemo- and Bioinformatics.


Automation and improved annotation interfaces will make CiTO more useful. CiTO:cites and CiTO:isCitedBy could used to mark up existing relationships in digital libraries such as ACM Digital Library and CiteSeer, and could enhance collections like Google Books and Mendeley, to make human navigation and automated use easier. To capture more sophisticated relationships, David Shotton has hopes of authors marking up citations before submitting papers; if it’s required, anything is possible. Data curators and article commentators may observe contradictions between papers, or methodology reuses; in these cases CiTO could be layered with an annotation ontology such as AO in order to make the provenance of such assertions clear.

CiTO could put pressure on existing publishers and information providers to improve their data services, perform more data cleanup, or to exposing bibliographies in open formats. Improved tools will be needed, as well as communities that are willing to add data by hand, and algorithms for inferring deep citation relationships.

One remaining challenge is aggregation of CiTO relationships between bibliographic data providers; article identifiers such as DOI are unfortunately not universal, and the bibliographic environment is messy, with many types of items, from books to theses to white papers to articles to reports. CiTO and related ontologies will help explicitly show the bibliographic web and relationships between these items, on the web of (meta)data.

Further Details

CiTO is part of an ecosystem of citations called Semantic Publishing and Referencing Ontologies (SPAR); see also the JISC Open Citation Project which is taking bibliographic data to the Web, and the JISC Open Bibliography Project. For those familiar with Shotton’s earlier writing on CiTO, note that SPAR breaks out some parts of the earlier formulation of this ontology.

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Posted in argumentative discussions, books and reading, information ecosystem, library and information science, PhD diary, scholarly communication, semantic web | Comments (3)